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Gut microbiome testing

The why and the how
23 May 2026 by
Biomh

Gut microbiome testing is on the rise


That is not surprising, because research has increasingly shown how important the gut microbiome is for human health. The gut microbiome has been linked to immunity, metabolism and obesity, mental health, and chronic disease.


What is the gut microbiome?


The gut microbiome refers to the collection of microorganisms living in the gastrointestinal tract. Although every person has a unique microbial profile, a healthy microbiome typically contains thousands of species, dominated by bacterial phyla such as Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria.


Essential functions

These microorganisms perform a number of vital functions for the human body, including:


  • Breaking down complex carbohydrates and fiber into short-chain fatty acids (SCFAs)
  • Producing essential vitamins such as B12, K2, and folate
  • Training and regulating the immune system
  • Maintaining the gut lining and helping prevent intestinal permeability
  • Protecting against pathogens by competing for resources
  • Communicating with the brain through the gut-brain axis

How does microbiome testing work?

By mapping the gut microbiome, we can gain insight into how well these functions may be supported in an individual. In that sense, the microbiome can serve as an important indicator of overall health. Using newer techniques such as 16S rRNA gene sequencing and shotgun metagenomics, researchers are now able to identify and quantify microbial species more quickly and accurately than ever before.


Well-designed microbiome tests can provide several types of useful information. They can offer insight into the diversity and composition of the gut microbiome, identify imbalances, and provide practical starting points for targeted dietary and lifestyle interventions.


It is still early days

At the same time, we have to be honest: this field is still in its early stages.

We still do not fully know what a “healthy” gut microbiome looks like for every individual. There is a lot we do not understand yet. But that should not stop us from starting to use and explore this technology. Even if the science is still evolving, it offers a framework. And for many people, especially those dealing with chronic or unexplained symptoms, that framework in combination with dietary adjustments and targeted supplementation has already been incredibly valuable.


The InnerBudies Gut Microbiome Test


The InnerBudies Gut Microbiome Test uses high-resolution sequencing to measure clinically relevant gut bacteria linked to digestion, metabolism, immunity, inflammation, and long-term gut health. It captures beneficial and imbalance-associated species to convert raw microbiome data into personalized health insights.


The test maps:


  1. Microbiome diversity


    1. Diversity reflects the richness and balance of gut bacteria. Higher diversity is generally associated with resilience, metabolic flexibility, and lower inflammation, while low diversity may indicate instability and gut imbalance.

  2. Positive bacteria


    1. Beneficial bacteria support fiber fermentation, butyrate production, gut barrier integrity, and anti-inflammatory activity. They are associated with digestive comfort, metabolic health, and microbiome stability.

  3. Negative bacteria


    1. Overrepresented negative bacteria may be linked to dysbiosis, inflammation, reduced diversity, and unfavorable metabolic activity. Overall health depends on microbial balance, not a single species in isolation.

  4. Microbial pathways


    1. Pathways reflect the metabolic functions of the microbiome, including fermentation, vitamin synthesis, SCFA production, bile acid metabolism, and inflammation regulation. This functional layer makes microbiome analysis more actionable and clinically relevant.

  5. Target group longevity


    1. This profile reflects microbiome patterns associated with healthy aging, metabolic resilience, and stable inflammation control. It serves as a strategic target for personalized microbiome optimization.

  6. Gut Microbiome Health Index (GMHI)


    1. GMHI is a composite score showing how closely a microbiome aligns with healthier versus dysbiotic ecosystem patterns. Higher scores suggest stronger microbial balance; lower scores highlight opportunities for targeted nutrition and lifestyle intervention.


  7. BUY THE INNERBUDIES GUT MICROBIOME TEST